From BITS wiki
Jump to: navigation, search

The RDXplorer (Read Depth eXplorer) [1] is a computational tool for copy number variants (CNV) detection in whole human genome sequence data using read depth (RD) coverage. CNV detection is based on the Event-Wise Testing (EWT) algorithm recently published by our group ([2]). The read depth coverage is estimated in non-overlapping intervals (100bp Windows) across an individual genome based on the pileup generated by SAMTools.

  1. http://rdxplorer.sourceforge.net
  2. Seungtai Yoon, Zhenyu Xuan, Vladimir Makarov, Kenny Ye, Jonathan Sebat
    Sensitive and accurate detection of copy number variants using read depth of coverage.
    Genome Res: 2009, 19(9);1586-92
    [PubMed:19657104] ##WORLDCAT## [DOI] (I p)

[ BioWare | Main_Page ]