Exercise: Golub data set
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Go to parent Introduction to R/Bioconductor for analysis of microarray data#Tutorials
Load the data set Golub_Merge
from the package golubEsets
. Identify probesets that are differentially expressed between the ALL and AML forms of leukemia. Generate an MA-plot and a volcanoplot for the results. Make sure that the expression data is log-transformed before you start the analysis.
Note that the material for the Golub study came from four different sources. Are there systematic differences in expression between the sources?