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Simple Omnibus Format in Text (SOFT) is designed for rapid batch submission (and download) of data. SOFT is a simple line-based, plain text format, meaning that SOFT files may be readily generated from common spreadsheet and database applications. A single SOFT file can hold both data tables and accompanying descriptive information for multiple, concatenated Platforms, Samples, and/or Series records. Used by GEO.


There are actually four types of GEO SOFT file available:

GEO Platform (GPL) These files describe a particular type of microarray. They are annotation files.

GEO Sample (GSM) Files that contain all the data from the use of a single chip. For each gene there will be multiple scores including the main one, held in the VALUE column.

GEO Series (GSE) Lists of GSM files that together form a single experiment.

GEO Dataset (GDS) These are curated files that hold a summarised combination of a GSE file and its GSM files. They contain normalised expression levels for each gene from each sample (i.e. just the VALUE field from the GSM file).

Example

See example and explanation